Substances Information System: powerful online search engine for chemical substances further expanded

Accessible and reliable information is essential for assessing risks to workers, consumers and the environment. In addition, SIS supports the identification of alternative substances to replace hazardous ones, thereby helping to prevent occupational diseases and to promote safe and sustainable innovation in line with the Safe and Sustainable by Design approach.

Daily updates and a significantly expanded substances library

Since its introduction in 2019, SIS has been significantly further developed, both technically and in terms of content. Most recently, a fully automated daily data pipeline has been implemented. This ensures that data from all underlying sources is continuously updated, always providing users with access to the most up-to-date information.

Moreover, the substances library has been significantly expanded, from 1 million to 4 million substances. As a result, all substances with a CAS number are now included in the system. This offers a much more comprehensive overview and greatly enhances the applicability of SIS for policy development, regulatory oversight, research and prevention.

For substances for which little or no measurement data is available — the so-called data gaps — TNO is exploring how these gaps can be filled using modelled data based on similar substances. This approach enables improved risk estimates, even for substances that have been studied to a limited extent.

A unique, publicly accessible tool

SIS is a publicly accessible online tool for which access can be requested. Users can search by substance name or sector, after which the tool automatically consults a wide range of relevant websites and databases. The aggregated information is presented in a structured and user-friendly way, allowing users to quickly obtain a comprehensive overview that can

be directly applied to risk assessment, substitution of hazardous substances, innovation and prevention

Tailored solutions for companies and sectors

In addition to the public tool, TNO also offers tailored solutions for organisations. SIS data can, for example, be made directly available within companies’ own IT environments and systems. Furthermore, customised analyses and predictions can be performed using company-specific data. These insights support product innovation, process optimisation and the prevention of hazardous substance use. Would you like to know more about SIS and what it can mean for your organisation? Please contact us.

View SIS here: https://diamonds.tno.nl/projects/sis