Efficient Drug Development

TNO works with public and private parties to create and implement innovative technologies that make the process of drug development – from laboratory to patient – more efficient. This will make it possible to cut development costs and to get drugs to patients sooner.

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Our latest developments

9 resultaten, getoond 1 t/m 5

TNO helps accelerate drug development through insight

Informatietype:
Insight
14 November 2022

To find the most effective interventions for complex metabolic diseases, we must first understand the dynamics of disease onset and progression. Only then can key targets and optimal therapeutic windows for more effective treatment be defined. We spoke with Anita van den Hoek, Research Scientist for TNO Metabolic Health, about how TNO helps pharmaceutical companies accelerate drug development through better understanding of disease pathways.

TNO proves method for effective pediatric drug development

Informatietype:
Insight
14 November 2022

Safe and effective drug dosing for young children come with their own challenges. Up to the age of 18, a child’s metabolism can change significantly. And in the first two years of life, those ontogenic differences can be rapid and dramatic. TNO published its findings from the first drug disposition (mass balance/metabolite profiling) study to conclusively prove that microtracing with accelerator mass spectrometry (AMS) is an effective way to collect clinical data in these young patients. This AMS technology can also be the key to building up more data on drug interventions in pregnant and lactating mothers.

Functional microbiome analysis

Informatietype:
Article

TNO has a wide range of available tools to increase understanding of the impact and interaction of the microbiome on human health. Learn more.

Target safety assessment

Informatietype:
Article

Our unique set of assessments and web-based target triaging platform TargetTri, can help to make informed decision making easy with transparent, knowledge-driven expert views on target efficacy, safety liabilities, and risk mitigation.

PK Studies AMS

Informatietype:
Article

With TNO’s microtracer expertise, drug development becomes a streamlined and targeted process.