Oil and gas shortages are not only pushing up the prices of gas and petrol, but also plastics, medicines and cosmetics. To make our society less dependent on fossil fuels and combat climate change, the chemical industry needs to change radically. In recent years, TU Delft and TNO have laid the foundation for cleaner production processes in the chemical industry. The new e-Chem partnership is now taking this a step further by actually constructing a clean factory of the future.